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  2. Dermis - Wikipedia

    en.wikipedia.org/wiki/Dermis

    The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...

  3. Integumentary system - Wikipedia

    en.wikipedia.org/wiki/Integumentary_system

    The dermis is the underlying connective tissue layer that supports the epidermis. It is composed of dense irregular connective tissue and areolar connective tissue such as a collagen with elastin arranged in a diffusely bundled and woven pattern. The dermis has two layers: the papillary dermis and the reticular layer.

  4. Skin - Wikipedia

    en.wikipedia.org/wiki/Skin

    The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis provides tensile strength and elasticity to the skin through an extracellular matrix composed of collagen fibrils , microfibrils , and elastic fibers , embedded in hyaluronan and proteoglycans . [ 15 ]

  5. Stratum spinosum - Wikipedia

    en.wikipedia.org/wiki/Stratum_spinosum

    Histologic image showing a section of epidermis. Stratum spinosum labeled slightly below center. The stratum spinosum (or spinous layer/prickle cell layer) [1] is a layer of the epidermis found between the stratum granulosum and stratum basale. [2]

  6. Human skin - Wikipedia

    en.wikipedia.org/wiki/Human_skin

    The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis is tightly connected to the epidermis by a basement membrane. It also harbours many nerve endings that provide the sense of touch and heat.

  7. Dense irregular connective tissue - Wikipedia

    en.wikipedia.org/wiki/Dense_irregular_connective...

    This type of connective tissue is found mostly in the reticular layer (or deep layer) of the dermis. [3] It is also in the sclera and in the deeper skin layers. Due to high portions of collagenous fibers, dense irregular connective tissue provides strength, making the skin resistant to tearing by stretching forces from different directions.

  8. Stratum basale - Wikipedia

    en.wikipedia.org/wiki/Stratum_basale

    In a growing fetus, fingerprints form where the cells of the stratum basale meet the papillae of the underlying papillary layer of the dermis, resulting in the formation of the ridges on the fingers. Fingerprints are unique to each individual and are used for forensic analyses because the patterns do not change with the growth and aging processes.

  9. Free nerve ending - Wikipedia

    en.wikipedia.org/wiki/Free_nerve_ending

    Free nerve endings are unencapsulated and have no complex sensory structures. They are the most common type of nerve ending, and are most frequently found in the skin.They penetrate the dermis and end in the stratum granulosum.