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In people who develop active TB of the lungs, also called pulmonary TB, the TB skin test will often be positive. In addition, they will show all the signs and symptoms of TB disease, and can pass the bacteria to others. So, if a person with TB of the lungs sneezes, coughs, talks, sings, or does anything that forces the bacteria into the air ...
People with inactive or latent TB will not develop symptoms, unless they develop active TB. “The hibernating bacteria in those individuals can recur and cause illness in that person, 10, 15, 20 ...
Assessments of the activity of TB cannot be made accurately on the basis of a single radiograph alone. If there is any question of active TB, sputum smears must be obtained. Therefore, any applicant might have findings grouped in this category, but still have active TB as suggested by the presence of signs or symptoms of TB, or sputum smears ...
TB infection No disease: Positive reaction to tuberculin skin test Negative bacteriologic studies (if done) No clinical, bacteriologic, or radiographic evidence of TB 3: TB, clinically active: M. tuberculosis cultured (if done) Clinical, bacteriologic, or radiographic evidence of current disease 4: TB Not clinically active: History of episode(s ...
Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. [1] Infection of other organs can cause a wide range of symptoms. [8] Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze.
Prevention of TB involves screening those at high risk, early detection and treatment of cases, and prompt vaccination with the bacillus Calmette-Guérin (BCG) vaccine. [ 7 ] [ 8 ] [ 9 ] Those at high risk include household, workplace, and social contacts of people with active TB.
Symptomatic infections are apparent and clinical, whereas an infection that is active but does not produce noticeable symptoms may be called inapparent, silent, subclinical, or occult. An infection that is inactive or dormant is called a latent infection. [54] An example of a latent bacterial infection is latent tuberculosis.
In a recently published metaanalysis, [26] with data from both developed and developing countries, QuantiFERON-TB Gold In Tube had a pooled sensitivity for active TB of 81% and specificity of 99.2%, whereas T-SPOT.TB had a pooled sensitivity of 87.5% and specificity of 86.3%. In head-to-head comparisons, the sensitivity of IGRAs surpassed TST.