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Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
Synthetic androgens/anabolic steroids (AAS), like nandrolone (as an ester like nandrolone decanoate or nandrolone phenylpropionate), are agonists of the androgen receptor (AR) similarly to testosterone but are not usually used in HRT for transgender men or for androgen replacement therapy (ART) in cisgender men.
Androgens are synthesized in the testes, the ovaries, and the adrenal glands. Androgens increase in both males and females during puberty. [3] The major androgen in males is testosterone. [4] Dihydrotestosterone (DHT) and androstenedione are of equal importance in male development. [4] DHT in utero causes differentiation of the penis, scrotum ...
Hyperandrogenism is a medical condition characterized by high levels of androgens.It is more common in women than men. [4] Symptoms of hyperandrogenism may include acne, seborrhea, hair loss on the scalp, increased body or facial hair, and infrequent or absent menstruation.
Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy in which androgens, often testosterone, are supplemented or replaced. It typically involves the administration of testosterone through injections, skin creams, patches, gels, pills, or subcutaneous pellets.
Testosterone and the cardiovascular system are the effects that the male hormone testosterone has on the cardiovascular system. The predominant androgen in men, testosterone, has shown to substantially decline throughout the aging process. [1] [2] The decline in both serum and total testosterone with age have been linked to several disease ...
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