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[78] [9] This delay is caused by reduced gastrointestinal motility, and reduce area under curve and half-life by only 11% and 18%, respectively; as such, no dose adjustments or time-of-day restrictions are necessary. [9] Depending on condition being treated, duloxetine is taken once a day or twice a day. [4] [9]
[3] [34] It has been used to treat hirsutism at dosages ranging from 62.5 mg/day to 750 mg/day. [44] A study found that multiple dosages of flutamide significantly reduced hirsutism in women with polycystic ovary syndrome and that there were no significant differences in the effectiveness for dosages of 125 mg/day, 250 mg/day, and 375 mg/day.
Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [7] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [8] body dysmorphic disorder [9] [10] [11] and chronic pain. [7]
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