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Treatment plans may include immunotherapy treatments such as sublingual allergy drops or tablets or allergy shots administered at a doctor’s office. [13] [3] Curex generally sends a three-month supply of immunotherapy treatments to patients to start. [3] Curex doctors continually monitor and adjust treatments as necessary. [1]
Sublingual immunotherapy involves putting drops or a tablet of allergen extracts under the tongue, which are then absorbed through the lining of the mouth. Sublingual immunotherapy has been demonstrated to be effective against rhinoconjunctivitis and asthma symptoms. [16] This effectiveness, however, varies depending on the type of allergen. [16]
In 1992, ALK and Abello merged. In the 1990s, ALK was the first company to launch sublingual immunotherapy drops (allergy immunotherapy administered as droplets under the tongue). In recent years, ALK's research and development strategy has been focused on introducing a range of sublingual immunotherapy tablets (SLIT-tablets).
The sublingual route may also be used for vaccines against various infectious diseases. Thus, preclinical studies have found that sublingual vaccines can be highly immunogenic and may protect against influenza virus [4] [5] and Helicobacter pylori, [6] but sublingual administration may also be used for vaccines against other infectious diseases.
To a lesser extent, the evidence also supports the use of sublingual immunotherapy for rhinitis and asthma. [121] For seasonal allergies the benefit is small. [123] In this form the allergen is given under the tongue and people often prefer it to injections. [121] Immunotherapy is not recommended as a stand-alone treatment for asthma. [121]
Moreover, sublingual administration is thought to have the potential to induce mucosal immune responses in a broad range of tissues, including the genitourinary tract. [3] Accordingly, Uromune has been found to induce immune responses both systemically and in the genitourinary tract.
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