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Titin [5] (/ ˈ t aɪ t ɪ n /; also called connectin) is a protein that in humans is encoded by the TTN gene. [ 6 ] [ 7 ] The protein, which is over 1 μm in length, [ 8 ] functions as a molecular spring that is responsible for the passive elasticity of muscle .
Myotilin was originally identified as a novel alpha-actinin binding partner with two Ig-like domains, that localized to the Z-disc. [9] The I-type Ig-like domains reside at the C-terminal half, and are most homologous to Ig domains 2-3 of palladin and Ig domains 4-5 of myopalladin and more distantly related to Z-disc Ig domains 7 and 8 of titin.
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An A-4 Skyhawk unloaded from a ship at Tanjung Priok port. Operation Alpha (Indonesian: Operasi Alpha) (in Israel known as "פולינז" or Polines for Operation Alpha I in 1980 and "מזורקה" or Mazurka for Operation Alpha II in 1982) was a covert operation carried out by the Indonesian Air Force (Indonesian: Tentara Nasional Indonesia Angkatan Udara) between 1979 and 1982 to acquire 30 ...
Similar to titin, it is thought to act as a molecular ruler along for thin filament assembly. Several proteins important for the stability of the sarcomeric structure are found in the Z-line as well as in the M-band of the sarcomere. Actin filaments and titin molecules are cross-linked in the Z-disc via the Z-line protein alpha-actinin.
21393 Ensembl ENSG00000173991 ENSMUSG00000007877 UniProt O15273 O70548 RefSeq (mRNA) NM_003673 NM_011540 RefSeq (protein) NP_003664 NP_003664.1 NP_035670 Location (UCSC) Chr 17: 39.67 – 39.67 Mb Chr 11: 98.27 – 98.28 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Telethonin, also known as Tcap, is a protein that in humans is encoded by the TCAP gene. Telethonin is expressed in ...
Myomesin is bound to myosin at its N-terminal. Obscurin connects the myomesin dimers and binds to the C-terminal of titin. It is thought that the myomesin-titin interaction is vital for the execution of the mechanical functions of the Ser/Thr kinase domain of titin. [2] Myomesin is a protein family found in the M-line of the sarcomere structure.
Tintin and Alph-Art (French: Tintin et l'Alph-Art) is the unfinished twenty-fourth and final volume of The Adventures of Tintin, the comics series by Belgian cartoonist Hergé.