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A lymph node is an organized collection of lymphoid tissue, through which the lymph passes on its way back to the blood. Lymph nodes are located at intervals along the lymphatic system. Several afferent lymph vessels bring in lymph, which percolates through the substance of the lymph node, and is then drained out by an efferent lymph vessel.
At the origin of the fluid-return process, interstitial fluid—the fluid between the cells in all body tissues [2] —enters the lymph capillaries. This lymphatic fluid is then transported via progressively larger lymphatic vessels through lymph nodes, where substances are removed by tissue lymphocytes and circulating lymphocytes are added to ...
Upon entering the lumen of a lymphatic capillary, the collected fluid is known as lymph. Each lymphatic capillary carries lymph into a lymphatic vessel, which in turn connects to a lymph node, a small bean-shaped gland that filters and monitors the lymphatic fluid for infections. [1] Lymph is ultimately returned to the venous circulation.
The lymph percolates through the lymph node tissue and exits via an efferent lymph vessel. An efferent lymph vessel may directly drain into one of the (right or thoracic) lymph ducts, or may empty into another lymph node as its afferent lymph vessel. [6] Both the lymph ducts return the lymph to the blood stream by emptying into the subclavian veins
Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, [1] usually referring to the delivery of blood to a capillary bed in tissue. Perfusion may also refer to fixation via perfusion, used in histological studies.
Lymphatic vessels carry lymph, a colorless, watery fluid originating from interstitial fluid (fluid in the tissues) which is squeezed out of the blood vessels. The lymphatic system transports infection-fighting cells called lymphocytes, is involved in the removal of foreign matter and cell debris by phagocytes and is part of the body's immune ...
Lymph is present throughout the body, and circulates through lymphatic vessels. These drain into and from lymph nodes – afferent vessels drain into nodes, and efferent vessels from nodes. When lymph fluid enters a node, it drains into the node just beneath the capsule in a space called the subcapsular sinus.
The lymph flows through lymph capillaries to lymph nodes where bacteria and tissue debris are removed from the lymph, while various types of white blood cells (mainly lymphocytes) are added to the fluid. In addition the lymph which drains the small intestine contains fat droplets called chylomicrons after the ingestion of a fatty meal. [28]