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Lesions of the medial dorsal and anterior nuclei of the thalami and lesions of the mammillary bodies are commonly involved in amnesic syndromes in humans. [8] Mammillary body atrophy is present in several other conditions, such as colloid cysts in the third ventricle, Alzheimer's disease, schizophrenia, heart failure, and sleep apnea. In spite ...
In neuroanatomy, the lateral geniculate nucleus (LGN; also called the lateral geniculate body or lateral geniculate complex) is a structure in the thalamus and a key component of the mammalian visual pathway. It is a small, ovoid, ventral projection of the thalamus where the thalamus connects with the optic nerve. There are two LGNs, one on the ...
A major output goes via the fornix to the lateral septal area and to the mammillary body of the hypothalamus (which the fornix interconnects with the hippocampus). [21] The hippocampus receives modulatory input from the serotonin , norepinephrine , and dopamine systems, and from the nucleus reuniens of the thalamus to field CA1.
The anterior nuclei receive afferents from the hippocampus and subiculum directly via the fornix, and indirectly via the mammillary bodies and mammillothalamic tract (MTT). They send efferent fibers to the cingulate gyrus, limbic, and orbitofrontal cortex. [1] The anterior nuclei of the thalamus display functions pertaining to memory.
The epithalamus is associated with sleep disorders like insomnia revolving around circadian rhythms of sleep wake cycles. The close connection of the epithalamus with the limbic system regulates the secretion of melatonin by the pineal gland and the regulation of motor pathways and emotions. [9] The secretion of melatonin happens in a cycle.
The diencephalon has also been known as the tweenbrain in older literature. [2] It consists of structures that are on either side of the third ventricle, including the thalamus, the hypothalamus, the epithalamus and the subthalamus. The diencephalon is one of the main vesicles of the brain formed during embryogenesis.
The mammillary bodies directly or indirectly connect to the amygdala, hippocampus, and thalami as major structures in the limbic system. [6] The mammillothalamic tract carries signals from the mammillary bodies via the anterior thalamus to support spatial memory .
The dorsal tegmental nucleus is located in the brain stem near the midline. Two nuclei exist in both hemispheres. The DTN is generally subdivided into four parts called partes centralis, ventromedialis, anterior, and posterior. [1] DTN contains a dense population of GABAergic cells. [2] [3] In the rat, few also express calbindin (CB) or ...