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Anticholinergic drugs are used to treat a variety of conditions: Dizziness (including vertigo and motion sickness-related symptoms) Extrapyramidal symptoms, a potential side-effect of antipsychotic medications; Gastrointestinal disorders (e.g., peptic ulcers, diarrhea, pyloro spasm, diverticulitis, ulcerative colitis, nausea, and vomiting)
Most common CNS disorders are highly polygenic in nature; that is, they are controlled by complex interactions between numerous gene products. As such, these conditions do not exhibit the single gene defect basis that is so attractive for the development of highly-specific drugs largely free of major undesirable side-effects ("the magic bullet ...
The effect is to prevent spasms of the stomach, intestine or urinary bladder. Both dicyclomine and hyoscyamine are antispasmodic due to their anticholinergic action. [medical citation needed] Both of these drugs have side effects common to anticholinergics and can worsen gastroesophageal reflux disease (GERD). [2]
Drug-induced arrhythmia worsened by anticholinergics' side effect of tachycardia. Parkinson's disease, e.g. levodopa. Atropine decreases the absorption of levodopa. Preventing travel sickness, relieve stomach cramps or spasms, e.g. hyoscine. Additive effect. Nausea and vomiting, e.g. cyclizine. Additive effect.
The most prominent side effects are dizziness and sleepiness. [41] Diphenhydramine is a potent anticholinergic agent and potential deliriant in higher doses. This activity is responsible for the side effects of dry mouth and throat, increased heart rate, pupil dilation, urinary retention, constipation, and, at high doses, hallucinations or ...
Common Examples Mechanism of benefit and effect Side effects, caution & contraindications Remarks Beta-blockers: Metoprolol; Atenolol; Bisoprolol; Block beta-1 receptors in the heart → stop the effects of catecholamines on the heart→ reduce heart rate, heart contractility and conduction velocity → reduce the workload of the heart [15 ...
The drug regulates behaviour and thoughts, and can also exhibit an anti-depressive effect. [3] [8] The side effect profile is similar to related antipsychotic agents, displaying weight gain, mental distress, and inability to sit still. Other possible symptoms include anticholinergic side effects such as insomnia, blurred vision, and dry mouth.
Dry throat is the most common side effect. If the medication gets in contact with the eyes, it may cause blurred vision for a brief time. The use of anticholinergics in combination with short-acting β 2-adrenergic agonists has been shown to reduce hospital admissions in children and adults with acute asthma exacerbations. [4] [5]