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The signs and symptoms of frontal lobe disorder can be indicated by dysexecutive syndrome [7] which consists of a number of symptoms which tend to occur together. [8] Broadly speaking, these symptoms fall into three main categories; cognitive (movement and speech), emotional or behavioral.
Negative symptoms are tied to potential dysfunction in the frontal lobe. While neuroimaging studies have yielded inconsistent results regarding brain volume, metabolism, and blood flow, functional neuroimaging during specific tasks demonstrates underactivation of the frontal cortex in schizophrenia.
The most frequent cause of the syndrome is brain damage to the frontal lobe. Brain damage leading to the dysexecutive pattern of symptoms can result from physical trauma such as a blow to the head or a stroke [6] or other internal trauma. It is important to note that frontal lobe damage is not the only cause of the syndrome.
Executive dysfunction characterizes many of the symptoms observed in numerous clinical populations. In the case of acquired brain injury and neurodegenerative diseases there is a clear neurological etiology producing dysexecutive symptoms.
The Wisconsin Card Sorting Test (WCST) can be used in conjunction with other tests to speculate to possible dysfunction of the prefrontal cortex, the front-most area of the frontal lobe, that plays an important role in executive functioning. However, since the age of modern medicine and brain imaging, the WCST has been purported to be ...
The dorsolateral prefrontal cortex (DLPFC or DL-PFC) is an area in the prefrontal cortex of the primate brain. It is one of the most recently derived parts of the human brain. It undergoes a prolonged period of maturation which lasts into adulthood. [1] The DLPFC is not an anatomical structure, but rather a functional one.
Neurological imaging has shown that TMoA is typically caused by an infarct of the anterior superior frontal lobe in the perisylvian area [6] of the left, or language-dominant, hemisphere. [1] The anterior superior frontal lobe is known as the prefrontal cortex which is responsible for the initiation and ideation of verbal speech. [7]
In neuroscience, the default mode network (DMN), also known as the default network, default state network, or anatomically the medial frontoparietal network (M-FPN), is a large-scale brain network primarily composed of the dorsal medial prefrontal cortex, posterior cingulate cortex, precuneus and angular gyrus.