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The Root effect is a physiological phenomenon that occurs in fish hemoglobin, named after its discoverer R. W. Root.It is the phenomenon where an increased proton or carbon dioxide concentration (lower pH) lowers hemoglobin's affinity and carrying capacity for oxygen.
In hemoglobin, the iron is in one of four heme groups and has six possible coordination sites; four are occupied by nitrogen atoms in a porphyrin ring, the fifth by an imidazole nitrogen in a histidine residue of one of the protein chains attached to the heme group, and the sixth is reserved for the oxygen molecule it can reversibly bind to. [5]
Human iron metabolism is the set of chemical reactions that maintain human homeostasis of iron at the systemic and cellular level. Iron is both necessary to the body and potentially toxic. Controlling iron levels in the body is a critically important part of many aspects of human health and disease.
A food chain is a linear system of links that is part of a food web, and represents the order in which organisms are consumed from one trophic level to the next. Each link in a food chain is associated with a trophic level in the ecosystem.
Food chain in a Swedish lake. Osprey feed on northern pike, which in turn feed on perch which eat bleak which eat crustaceans.. A food chain is a linear network of links in a food web, often starting with an autotroph (such as grass or algae), also called a producer, and typically ending at an apex predator (such as grizzly bears or killer whales), detritivore (such as earthworms and woodlice ...
In mammals, hemoglobin makes up about 96% of a red blood cell's dry weight (excluding water), and around 35% of the total weight (including water). [5] Hemoglobin has an oxygen-binding capacity of 1.34 mL of O 2 per gram, [ 6 ] which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood plasma alone. [ 7 ]
For example, a methemoglobin concentration of 1.5 g/dL may represent a percentage of 10% in an otherwise healthy patient with a baseline hemoglobin of 15 mg/dL, whereas the presence of the same concentration of 1.5 g/dL of methemoglobin in an anemic patient with a baseline hemoglobin of 8 g/dL would represent a percentage of 18.75%.
A fish's hypoxia tolerance can be represented in different ways. A commonly used representation is the critical O 2 tension (P crit), which is the lowest water O 2 tension (P O 2) at which a fish can maintain a stable O 2 consumption rate (M O 2). [2]