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It has been proven to be effective in various inflammatory skin diseases, e.g., seborrheic dermatitis, [2] cutaneous lupus erythematosus, [3] oral lichen planus, [4] vitiligo, [5] and psoriasis. [6] [7] Tacrolimus and pimecrolimus are both calcineurin inhibitors and function as immunosuppressants. [8]
Lichen planus may be categorized as affecting mucosal or cutaneous surfaces.. Cutaneous forms are those affecting the skin, scalp, and nails. [10] [11] [12]Mucosal forms are those affecting the lining of the gastrointestinal tract (mouth, pharynx, esophagus, stomach, anus), larynx, and other mucosal surfaces including the genitals, peritoneum, ears, nose, bladder and conjunctiva of the eyes.
Ocular effects: Topical steroid drops are frequently used after eye surgery but can also raise intraocular pressure (IOP) and increase the risk of glaucoma, cataract, retinopathy as well as systemic adverse effects. [14] Tachyphylaxis: The acute development of tolerance to the action of a drug after repeated doses. [15]
Dr. Michael Chancellor, Lipella’s Chief Medical Officer and author of the paper, commented, “Oral lichen planus is a chronic inflammatory condition that significantly impacts patients' quality of life. Traditional therapies, primarily topical corticosteroids, often lead to undesirable side effects with long-term use.
Treatment: Lichen planus doesn't have a cure, but some treatments can make you feel more comfortable and speed up the healing process. Those include antihistamines and topical or oral steroids ...
Lichen planus is an inflammatory skin disease. When it affects the scalp, it’s called lichen planopilaris . There’s a lot we don’t know about lichen planus and lichen planopilaris, but they ...