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Ehrlichiosis (/ ˌ ɛər l ɪ k i ˈ oʊ s ɪ s /; also known as canine rickettsiosis, canine hemorrhagic fever, canine typhus, tracker dog disease, and tropical canine pancytopenia) is a tick-borne disease of dogs usually caused by the rickettsial agent Ehrlichia canis. Ehrlichia canis is the pathogen of animals.
E. canis is a small, coccus bacterium with a single circular chromosome.Minute in size, E. canis is smaller than the other species in the genus Ehrlichia. [8] [10]The cell walls of this organism lack peptidoglycans and lipopolysaccharides typically present in at least small amounts in most other Gram-negative bacteria, which is believed to contribute to its ability to resist the immune ...
Dogs infected with Ehrlichia often show lameness, lethargy, enlarged lymph nodes, and loss of appetite during the acute phase, which is one to three weeks after infection. Other symptoms include cough, diarrhea, vomiting, abnormal bruising and/or bleeding, fever, and loss of balance.
Ehrlichia canis is a small, obligate-intracellular, tick-transmitted, Gram-negative α-proteobacterium. This species is responsible for the globally distributed canine monocytic ehrlichiosis . E. canis also shows evolution in its complex membrane structures and immune evasion strategies.
Breed, lack of water, exercise, and high ambient temperature predispose dogs to heat stroke. Signs include vomiting, diarrhea, collapse, difficulty breathing, and body temperature approaching 42 °C to 43 °C. Treatment includes cooling the dogs with wet towels and fans, intravenous fluid therapy, and other supportive care. [171]
Enrofloxacin, sold under the brand name Baytril, among others, is a fluoroquinolone antibiotic used for the treatment of animals. [1] It is a bactericidal agent. [1]The bactericidal activity of enrofloxacin is concentration-dependent, with susceptible bacteria cell death occurring within 20–30 minutes of exposure.