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Retinol, also called vitamin A 1, is a fat-soluble vitamin in the vitamin A family that is found in food and used as a dietary supplement. [3] Retinol or other forms of vitamin A are needed for vision, cellular development, maintenance of skin and mucous membranes , immune function and reproductive development. [ 3 ]
Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [8] [9] [10] For acne, it is applied to the skin as a cream, gel or ointment. [10]
Retinol-binding protein 4 has been a drug target for eye diseases as RBP4 is the sole carrier for retinol, which is an essential nutrient for the visual cycle. Animal studies using RBP4-antagonists showed that lowering RBP4 can lead to reduction in the accumulation of lipofuscin that leads to vision loss in eye diseases like Stargardt's disease ...
Retinoid receptors are type II nuclear receptors (a class of proteins) that bind to retinoids.When bound to a retinoid, they act as transcription factors, altering the expression of genes with corresponding response elements.
Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]
Before undergoing surgery, a subject should avoid long periods of fasting. Oral feeding should be established as soon as possible after surgery. Other aspects of nutrition such as control of glucose, reduction in risk factors that causes stress-related catabolism or impairment of gastrointestinal functions, and encourage early physical activity ...