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  2. DNA polymerase - Wikipedia

    en.wikipedia.org/wiki/DNA_polymerase

    Retroviruses encode an unusual DNA polymerase called reverse transcriptase, which is an RNA-dependent DNA polymerase (RdDp) that synthesizes DNA from a template of RNA. The reverse transcriptase family contain both DNA polymerase functionality and RNase H functionality, which degrades RNA base-paired to DNA. An example of a retrovirus is HIV. [14]

  3. RNA polymerase - Wikipedia

    en.wikipedia.org/wiki/RNA_polymerase

    RNA polymerase (purple) unwinding the DNA double helix. It uses one strand (darker orange) as a template to create the single-stranded messenger RNA (green). In molecular biology , RNA polymerase (abbreviated RNAP or RNApol ), or more specifically DNA-directed/dependent RNA polymerase ( DdRP ), is an enzyme that catalyzes the chemical reactions ...

  4. DNA - Wikipedia

    en.wikipedia.org/wiki/DNA

    To begin transcribing a gene, the RNA polymerase binds to a sequence of DNA called a promoter and separates the DNA strands. It then copies the gene sequence into a messenger RNA transcript until it reaches a region of DNA called the terminator , where it halts and detaches from the DNA.

  5. Polymerase - Wikipedia

    en.wikipedia.org/wiki/Polymerase

    Structure of Taq DNA polymerase. In biochemistry, a polymerase is an enzyme (EC 2.7.7.6/7/19/48/49) that synthesizes long chains of polymers or nucleic acids. DNA polymerase and RNA polymerase are used to assemble DNA and RNA molecules, respectively, by copying a DNA template strand using base-pairing interactions or RNA by half ladder replication.

  6. Central dogma of molecular biology - Wikipedia

    en.wikipedia.org/wiki/Central_dogma_of_molecular...

    A second version of the central dogma is popular but incorrect. This is the simplistic DNA → RNA → protein pathway published by James Watson in the first edition of The Molecular Biology of the Gene (1965). Watson's version differs from Crick's because Watson describes a two-step (DNA → RNA and RNA → protein) process as the central ...

  7. Primary transcript - Wikipedia

    en.wikipedia.org/wiki/Primary_transcript

    This DNA strand is bound by an RNA polymerase at the promoter region of the DNA. [2] Transcription of DNA by RNA polymerase to produce primary transcript. In eukaryotes, three kinds of RNA—rRNA, tRNA, and mRNA—are produced based on the activity of three distinct RNA polymerases, whereas, in prokaryotes, only one RNA polymerase exists to ...

  8. RNA-dependent RNA polymerase - Wikipedia

    en.wikipedia.org/wiki/RNA-dependent_RNA_polymerase

    This is in contrast to typical DNA-dependent RNA polymerases, which all organisms use to catalyze the transcription of RNA from a DNA template. RdRp is an essential protein encoded in the genomes of most RNA-containing viruses that lack a DNA stage, [ 1 ] [ 2 ] including SARS-CoV-2 .

  9. Reading frame - Wikipedia

    en.wikipedia.org/wiki/Reading_frame

    Any given sequence of DNA can therefore be read in six different ways: Three reading frames in one direction (starting at different nucleotides) and three in the opposite direction. During transcription, the RNA polymerase read the template DNA strand in the 3′→5′ direction, but the mRNA is formed in the 5′ to 3′ direction. [3]