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Feathery degeneration - large cells with pale flocculant cytoplasm (left-bottom and right-top). H&E stain . In histo pathology , feathery degeneration , formally feathery degeneration of hepatocytes , is a form of liver parenchymal cell (i.e. hepatocyte ) death associated with cholestasis .
This tumor is the result of a congenital arteriovenous malformation hepatocyte response. This process is one in which all normal constituents of the liver are present, but the pattern by which they are presented is abnormal. [citation needed] These tumors usually do not have any symptoms. If large, they may present with abdominal pain. [2]
Histopathology of a ballooning hepatocyte.png, H&E stain. Ballooning degeneration centre-left and centre-right. H&E stain. A Councilman body can also be seen in the upper-right of the section. In histo pathology, ballooning degeneration, formally ballooning degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death.
Fatty liver can develop into hepatic fibrosis, cirrhosis or liver cancer. [8] For people affected by NAFLD, the 10-year survival rate was about 80%. The rate of progression of fibrosis is estimated to be one per 7 years in NASH and one per 14 years in NAFLD, with an increasing speed.
Councilman body (upper-right) and ballooning degeneration (centre-left). H&E stain. In pathology, a Councilman body, also known as a Councilman hyaline body or apoptotic body, is an eosinophilic globule of apoptotic hepatocyte cell fragments. Ultimately, the fragments are taken up by macrophages or adjacent parenchymal cells. [1]
Elevated alkaline phosphatase in patients with cancer normally spans [clarification needed] throughout the bones or liver. Metastases that exist in the lung, breast, prostate, colon, thyroid, and further organs can also enter the liver or bone. [ 12 ]
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