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  2. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    apixaban: anticoagulant: Eliquis 9872 7395 4 lenalidomide: multiple myeloma: Revlimid 9685 8187 5 nivolumab: oncology: Opdivo 7570 5763 6 pembrolizumab: oncology: Keytruda 7171 3809 7 etanercept: rheumatoid arthritis: Enbrel 7126 7885 8 trastuzumab: breast cancer: Herceptin 6981 7013 9 bevacizumab: colon cancer: Avastin 6847 6686 10 rituximab ...

  3. Is Eliquis Covered by Medicare? - AOL

    www.aol.com/eliquis-covered-medicare-140000963.html

    How much does Eliquis cost with Medicare? According to the manufacturer of Eliquis, in 2024, the list price for a 30-day supply of Eliquis is $594 , but people on Medicare pay, on average, $55 per ...

  4. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and clot-bound factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. [ 28 ]

  5. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  6. Gen Z’s expensive drug habit: More want brand-name ... - AOL

    www.aol.com/finance/gen-z-expensive-drug-habit...

    Gen Z is most likely to prefer brand-name drugs—despite being an average 79% more expensive than their generic counterparts—according to a Tebra survey published in January 2025.

  7. Medicare targets popular weight loss drugs Ozempic, Wegovy ...

    www.aol.com/medicare-targets-popular-weight-loss...

    Medicare will seek to negotiate lower list prices for the blockbuster diabetes and weight loss drugs Ozempic and Wegovy and 14 other medications, a cost-saving move that would take effect in 2027.

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