Search results
Results From The WOW.Com Content Network
A Lindbergh perfusion pump, c. 1935, an early device for simulating natural perfusion. Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, [1] usually referring to the delivery of blood to a capillary bed in tissue. Perfusion may also refer to fixation via perfusion, used in histological ...
Reperfusion injury, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused when blood supply returns to tissue (re-+ perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia).
An increasingly poor match between ventilation and perfusion is seen with age, as well as a decreased ability to compensate for hypoxic states. [8]: 646 Diseases that affect the pulmonary interstitium can also result in hypoxia, by affecting the ability of oxygen to diffuse into arteries.
Ischemia can be partial (poor perfusion) or total blockage. The inadequate delivery of oxygenated blood to the organs must be resolved either by treating the cause of the inadequate delivery or reducing the oxygen demand of the system that needs it.
Ventilation/perfusion matching: under-ventilated lung usually has a low oxygen content which leads to localized vasoconstriction limiting blood flow to that lung tissue. Supplemental oxygen abolishes this constriction, leading to poor ventilation/perfusion matching. This redistribution of blood to areas of the lung with poor ventilation reduces ...
A decrease in perfusion relative to ventilation (as occurs in pulmonary embolism, for example) is an example of increased dead space. [12] Dead space is a space where gas exchange does not take place, such as the trachea; it is ventilation without perfusion. A pathological example of dead zone would be a capillary blocked by an embolus.
Ischemia can be a partial (poor perfusion) or total blockage. Compartment syndrome is a condition in which increased pressure within one of the body's anatomical compartments results in insufficient blood supply to tissue within that space. [31] [32] There are two main types: acute and chronic. [31] Compartments of the leg or arm are most ...
End organ damage is severe impairment of major body organs due to systemic disease. Commonly this is referred to in diabetes, high blood pressure, or states of low blood pressure or low blood volume. [1]