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Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the fatty layer under the skin – panniculus adiposus). [1] Symptoms include tender skin nodules , and systemic signs such as weight loss and fatigue .
The exact cause of lipodermatosclerosis is unknown. [3] [6] Venous disease, such as venous incompetence, venous hypertension, and body mass may be relevant to the underlying pathogenesis. [3] Increased blood pressure in the veins (venous hypertension) can cause diffusion of substances, including fibrin, out of capillaries.
Erythema nodosum (EN) is an inflammatory condition characterized by inflammation of subcutaneous fat tissue, resulting in painful red/blue lumps or nodules that are usually seen symmetrically on both shins, on the thighs, arms, and elsewhere. [1]
Erythema induratum is a panniculitis on the calves. It occurs mainly in women, but it is very rare now. It occurs mainly in women, but it is very rare now. Historically, when it has occurred, it has often been concomitant with cutaneous tuberculosis , and it was formerly thought to be always a reaction to the TB bacteria .
Although the age at which the disease manifests itself varies as well, most patients are between 30 and 60 years old. [3] The median age was 41 years old in a set of 40 cases, [6] and 42 years old in another Spanish series. [3] Asian patients appear to be affected by lupus erythematosus panniculitis at a slightly younger age group, with a mean ...
Weber–Christian disease is a cutaneous condition characterized by recurrent subcutaneous nodules that heal with depression of the overlying skin. [1] It is a type of panniculitis. [2] It is a rare disease seen in females 30–60 years of age. It is a recurring inflammation of fatty layers of tissue present beneath the skin.
About 30,000 cases of Lyme disease in the U.S. are reported to the Centers for Disease Control and Prevention by state and local health departments each year. However, the CDC says that many more ...
Septal panniculitis is a condition of the subcutaneous fat affecting the layer of adipose tissue that lies between the dermis and underlying fascia, of which there are two forms: acute erythema nodosum and chronic erythema nodosum.