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The GI cocktail is a mixture of a viscous anesthetic, an antacid, and an anticholinergic. [1] [2] Common viscous anesthetics use are viscous lidocaine or xylocaine.Common antacids used are magnesium hydroxide, aluminum hydroxide, or simethicone (more commonly known as Mylanta or Maalox). [3]
Lidocaine is an antiarrhythmic medication of the class Ib type. [7] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [10] [7] When injected near nerves, the nerves cannot conduct signals to or from the brain. [8] Lidocaine was discovered in 1946 and went on sale in 1948. [11]
Lidocaine/prilocaine is a eutectic mixture of equal quantities (by weight) of lidocaine and prilocaine. A 5% emulsion preparation, containing 2.5% each of lidocaine/prilocaine, is marketed by APP Pharmaceuticals under the trade name EMLA (an abbreviation for Eutectic Mixture of Local Anesthetics ). [ 5 ]
The SI unit of kinematic viscosity is square meter per second (m 2 /s), whereas the CGS unit for kinematic viscosity is the stokes (St, or cm 2 ·s −1 = 0.0001 m 2 ·s −1), named after Sir George Gabriel Stokes. [29] In U.S. usage, stoke is sometimes used as the singular form.
For kinematic viscosity, the SI unit is m^2/s. In engineering, the unit is usually Stoke or centiStoke, with 1 Stoke = 0.0001 m^2/s, and 1 centiStoke = 0.01 Stoke. For liquid, the dynamic viscosity is usually in the range of 0.001 to 1 Pascal-second, or 1 to 1000 centiPoise.
Aside from its use as a dental anesthetic, procaine is used less frequently today, since more effective (and hypoallergenic) alternatives such as lidocaine (Xylocaine) exist. Like other local anesthetics (such as mepivacaine , and prilocaine ), procaine is a vasodilator, thus is often coadministered with epinephrine for the purpose of ...