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  2. Management of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Management_of_HIV/AIDS

    Furthermore, the PARTNER study, [43] which ran from 2010 to 2014, enrolled 1166 serodiscordant couples (where one partner is HIV positive and the other is negative) in a study that found that the estimated rate of transmission through any condomless sex with the HIV-positive partner taking ART with an HIV load less than 200 copies/ml was zero. [43]

  3. List of antiretroviral fixed-dose combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_antiretroviral...

    Antiretroviral drugs are used to manage HIV/AIDS. Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden. Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.

  4. List of antiviral drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_antiviral_drugs

    HIV Mylan: NNRTI 1998 Elvitegravir: HIV Gilead Sciences Integrase inhibitor 2012 (Fixed-dose combo Stribild) 2014 (single pill) 2015 ; Emtricitabine: HIV Gilead Sciences NRTI 2003 Enfuvirtide: HIV Entry inhibitor 2003 Ensitrelvir: COVID-19: Shionogi: 3C-like protease inhibitor Entecavir: HIV NRTI 2005 Etravirine (Intelence) [8] HIV NNRTI 2008 ...

  5. Reverse-transcriptase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Reverse-transcriptase...

    An example of this is K103N and K101E which sit at the entrance of the pocket, [18] [19] blocking the entrance/binding of the drug. A second mechanism is the disruption of important interactions on the inside of the pocket. For example, Y181C and Y188L result in the loss of important aromatic rings involved in NNRTI binding.

  6. HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/HIV/AIDS

    In the United States, intravenous drug users made up 12% of all new cases of HIV in 2009, [74] and in some areas more than 80% of people who inject drugs are HIV-positive. [18] HIV is transmitted in about 90% of blood transfusions using infected blood. [46]

  7. Integrase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Integrase_inhibitor

    Raltegravir (Isentress), developed by Merck & Co., was the first INSTI approved by the FDA in October 2007.; Elvitegravir (Vitekta), licensed by Gilead Sciences from Japan Tobacco, was approved by the U.S. Food and Drug Administration in August 2012, for use in adults starting HIV treatment for the first time as part of the fixed dose combination with emtricitabine and tenofovir disoproxil ...

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