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However, PKM2 contains an inducible nuclear localization signal in its C-terminal domain. The role of PKM2 within the nucleus is complex, since pro-proliferative but also pro-apoptotic stimuli have been described. On the one hand, nuclear PKM2 was found to participate in the phosphorylation of histone 1 by direct phosphate transfer from PEP to ...
A North American nuclear family. For social conservatism in the United States and Canada, the idea that the nuclear family is traditional is a very important aspect, where family is seen as the primary unit of society. These movements oppose alternative family forms and social institutions that are seen by them to undermine parental authority.
Nuclear Family is an American documentary miniseries directed and produced by Ry Russo-Young. It follows Russo-Young's mothers as an unexpected lawsuit sends shockwaves throughout their family's lives. It consisted of 3 episodes and premiered on September 26, 2021, on HBO. [1]
Nuclear envelope pore membrane protein POM 121 is a protein that in humans is encoded by the POM121 gene. [ 5 ] [ 6 ] [ 7 ] Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
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The SLOWPOKE research reactor was conceived in 1967 at the Whiteshell Laboratories of AECL. In 1970 a prototype unit called SLOWPOKE (both the name of the reactor and of the prototype reactor class of 2 reactors it was a member of; especially later when further generations of SLOWPOKE reactors had appeared, these type of reactors were named SLOWPOKE-1), was designed and built at Chalk River ...
The controversy has blown over by now (or has it?), but back when “Toy Story 4” came out, a certain contingent of the moviegoing public went nuclear when they discovered that Pixar had ...
The PFKFB3 promoter is predicted to contain multiple binding sites, including Sp-1 and AP-2 binding sites. It also contains motifs for the binding of E-box, nuclear factor-1 (NF-1), and progesterone response element. Expression of the promoter is shown to be induce by phorbol esters and cyclic-AMP-dependent protein kinase signaling. [10]