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Familial atrial fibrillation is an autosomal dominant heart condition that causes disruptions in the heart's normal rhythm. [ 1 ] [ 2 ] This condition is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria ), which causes the heartbeat to become fast and irregular.
Atrial fibrillation is associated with an increased risk of heart failure, dementia, and stroke. [3] [12] It is a type of supraventricular tachycardia. [14] Atrial fibrillation frequently results from bursts of tachycardia that originate in muscle bundles extending from the atrium to the pulmonary veins. [15]
The overall effect of each of the genetic variants associated with short QT syndrome is to shorten the cardiac action potential, which in turn increases the risk of developing abnormal heart rhythms including atrial fibrillation and ventricular fibrillation. [2]
Atrial fibrillation (A-fib). An irregular and often very fast heart rate. ... It can be caused by your genetics or conditions like diabetes and cancer. Stroke. A stroke is when part of your brain ...
A new expert report, published in the journal Stroke, reviews the latest research and explains that three common cardiovascular diseases in adults — heart failure, atrial fibrillation (AFib ...
Inherited sequence variants in human KCNE5 are associated with atrial fibrillation and Brugada syndrome. Atrial fibrillation is the most common chronic cardiac arrhythmia, affecting 2-3 million in the United States alone, predominantly in the aging population. A minority of cases are linked to ion channel gene mutations, whereas the majority ...