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Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride/kg body weight). [ 2 ] [ 3 ] [ 4 ] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 ...
Antifluoridationist literature links fluoride exposure to a wide variety of effects, including AIDS, allergy, Alzheimer's disease, arthritis, cancer, and low IQ, along with diseases of the gastrointestinal tract, kidney, pineal gland, and thyroid, though there is no scientific evidence linking fluoridation to these adverse health effects. [70] [71]
Most patients with skeletal fluorosis show side effects from the high fluoride dose such as ruptures of the stomach lining and nausea. [4] Fluoride can also damage the parathyroid glands, leading to hyperparathyroidism, the uncontrolled secretion of parathyroid hormones. These hormones regulate calcium concentration in the body.
The pineal gland (also known as the pineal body [1] or epiphysis cerebri) is a small endocrine gland in the brain of most vertebrates. It produces melatonin , a serotonin -derived hormone , which modulates sleep patterns following the diurnal cycles . [ 2 ]
In any case, it is only the fluoride that is directly present in the mouth (topical treatment) that prevents cavities; fluoride ions that are swallowed do not benefit the teeth. [3] Water fluoridation is the controlled addition of fluoride to a public water supply in an effort to reduce tooth decay in people who drink the water. [4]
The research had two goals: (1) to warn communities with a high concentration of fluoride of the danger, initiating a reduction of the fluoride levels in order to reduce incidence rates of fluorosis, and (2) to encourage communities with a low concentration of fluoride in drinking water to add fluoride in order to help prevent tooth decay. By ...
Kids whose mothers had higher levels of fluoride in their urine were 83% more likely to exhibit a range of neurobehavioral issues, including anxiety, emotional reactivity and physical complaints ...
[6] [7] Bottled water often has unknown fluoride levels. [8] Tooth decay affects 60–90% of schoolchildren worldwide. [9] Fluoridation reduces cavities in children, with Cochrane reviews estimating reductions of 35% in baby teeth and 26% in permanent teeth when no other fluoride sources are available, though efficacy in adults is less clear.