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[84] [85] There is 29–42% increase in congenital heart defects among children whose mothers were prescribed sertraline during pregnancy, [14] [15] with sertraline use in the first trimester associated with 2.7-fold increase in septal heart defects. [14] Abrupt interruption of sertraline treatment may result in withdrawal or discontinuation ...
A large cohort study suggested no substantial increase in the risk of cardiac malformations attributable to SSRI usage during the first trimester of pregnancy. [90] A number of large studies of people without known pre-existing heart disease have reported no EKG changes related to SSRI use. [91]
Gestational diabetes is a form of diabetes that is first diagnosed during pregnancy and can accordingly cause high blood sugar that affects the woman and the baby. [9] In 10 - 20% of women whose diet and exercise are not adequate enough to control blood sugar, insulin injections may be required to lower blood sugar levels. [ 9 ]
SSRIs are modern antidepressants often used as a first-line treatment for major depressive disorder. Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram).
In fact, positive antenatal screenings administered in the first or third trimester are found to be high risk factors for early cessation in breastfeeding. [48] Studies also report that the environmental effects of maternal depression affect the developing fetus to such an extent that the impact can be seen during adulthood of the offspring.
Not all intimate issues that occur while using Zoloft are caused by Zoloft. Between 35 and 50 percent of people with major depressive disorder experience problems prior to treatment.
[23] [24] During absorption SSRIs bind to proteins and are widely distributed throughout the body, including the brain, whereas they are lipophilic. [25] Metabolism and elimination takes place mainly in the liver [ 24 ] and most of the SSRIs produce pharmacologically active metabolites, [ 26 ] as demonstrated in table 3 among with other ...
These are some of my favorite pregnancy-safe exercises to build strength and improve mobility in the first trimester. Bonus: many of them help relieve back pain and improve stability in the low back.