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Microcytic anaemia; Microcytosis is the presence of red cells that are smaller than normal. Normal adult red cell has a diameter of 7.2 µm. Microcytes are common seen in with hypochromia in iron-deficiency anaemia, thalassaemia trait, congenital sideroblastic anaemia and sometimes in anaemia of chronic diseases.
The normochromic cells have a normal concentration of haemoglobin, and are therefore 'red enough' while the hypochromic cells do not; thus the value of the mean corpuscular hemoglobin concentration.The most common cause of microcytosis is iron deficiency anemia. Every time Hb synthesis being impaired in bone marrow microcytosis can occurs such ...
The most common causes of this kind of anemia are iron deficiency and thalassemia. Hypochromic anemia was historically known as chlorosis or green sickness for the distinct skin tinge sometimes present in patients, in addition to more general symptoms such as a lack of energy, shortness of breath, dyspepsia , headaches , a capricious or scanty ...
Of the drugs that cause DIL, hydralazine has been found to cause a higher incidence. Hydralazine is a medication used to treat high blood pressure. Approximately 5% of the patients who have taken hydralazine over long periods of time and in high doses have shown DIL-like symptoms. [8] Many of the other drugs have a low to very low risk to ...
Polycythemia has many causes. It can describe an increase in the number of red blood cells [ 1 ] ("absolute polycythemia") or to a decrease in the volume of plasma ("relative polycythemia"). [ 2 ] Absolute polycythemia can be due to genetic mutations in the bone marrow ("primary polycythemia"), physiologic adaptations to one's environment ...
Rare elliptocytes (less than 1%) on a peripheral blood smear are a normal finding. [citation needed]These abnormal red blood cells are seen in higher numbers in the blood films of patients with blood disorders such as: [4]
Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder which occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst , leading to an insufficient number of oxygen-carrying red blood cells in circulation . The lifetime of the RBCs is reduced from the normal 100–120 days to just a few days in ...
Pinocytosis, also known as cell drinking, is the absorption of small aqueous particles along with the membrane receptors that recognize them.It is an example of fluid phase endocytosis and is usually a continuous process within the cell.