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  2. Polycythemia - Wikipedia

    en.wikipedia.org/wiki/Polycythemia

    Treatment can include phlebotomy, aspirin, and myelosuppressive or cytoreductive medications based on risk stratification. [7] For secondary polycythemia, management involves addressing the underlying etiology of increased erythropoeitin production, such as smoking cessation, CPAP for sleep apnea, or removing any EPO-producing tumours. [6]

  3. Pacak–Zhuang syndrome - Wikipedia

    en.wikipedia.org/wiki/Pacak–Zhuang_syndrome

    The most common therapies for secondary polycythemia are phlebotomies [9] and, for paraganglioma and/or somatostatinoma in this cohort of patients, surgery accompanied by antihypertensive medication. [1] HIF-2α inhibitor belzutifan led to substantial improvement of symptoms in a patient with Pacak–Zhuang syndrome. [10]

  4. Polycythemia vera - Wikipedia

    en.wikipedia.org/wiki/Polycythemia_vera

    In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [2] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.

  5. Primary myelofibrosis - Wikipedia

    en.wikipedia.org/wiki/Primary_myelofibrosis

    It is indicated for the treatment of intermediate or high-risk myelofibrosis, including primary myelofibrosis or secondary myelofibrosis [post-polycythemia vera and post-essential thrombocythemia], in adults with anemia. [31] [32]

  6. Bomedemstat - Wikipedia

    en.wikipedia.org/wiki/Bomedemstat

    A third Imago-sponsored global clinical trial for the treatment of essential thrombocythemia was begun in 2020. [10] The results of this global study have also been presented at the American Society of Hematology and the European Hematology Association. A fourth trial begun in 2023 for the treatment of polycythemia vera is ongoing. [11]

  7. Myomatous erythrocytosis syndrome - Wikipedia

    en.wikipedia.org/wiki/Myomatous_erythrocytosis...

    Myomatous erythrocytosis syndrome (MES) is an uncommon gynecological disorder associated with isolated polycythemia and uterine fibroids.The primary feature of myomatous erythrocytosis syndrome is that hemoglobin goes back to its baseline level following the removal of the myoma.

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