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Methenamine, also known as hexamine or hexamethylenetetramine and sold under the brand names Hiprex, Urex, and Urotropin among others, is a urinary tract antiseptic and antibacterial medication which is used in the prevention of recurrent urinary tract infections (UTIs).
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
Recurrent urinary tract infections are defined as at least two infections (episodes) in a six-month time period or three infections in twelve months, can occur in adults and in children. [113] Cystitis refers to a urinary tract infection that involves the lower urinary tract (bladder).
Nitrofurantoin is pregnancy category A in Australia. [3] It is one of the few drugs commonly used in pregnancy to treat UTIs. [38] There is a potential risk of hemolytic anemia in the newborn when used near time of delivery. [3] Newborns of women given this drug late in pregnancy had a higher risk of developing neonatal jaundice. [39]
A UTI vaccine is a vaccine used for prevention of recurrent urinary tract infections (UTIs). [1] [2] A number of UTI vaccines have been developed and/or marketed.[1] [2] [3] These include Uromune (MV-140; sublingual spray), UroVaxom (OM-89, OM-8980; oral tablet), [4] Solco-Urovac (Strovac; vaginal suppository or intramuscular injection), [5] [6] ExPEC4V (V10, JNJ-63871860; intramuscular ...
Among women who consume any quantity of alcohol during pregnancy, the risk of giving birth to a child with FASD is about 15%, and to a child with FAS about 1.5%. Drinking 2 standard drinks a day, or 6 standard drinks in a short time, carries a 4.3% risk of a FAS birth (i.e. one of every 23 heavy-drinking pregnant women will deliver a child with ...
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