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Carbohydrate antigen 19-9 (CA19-9), also known as sialyl-Lewis A, is a tetrasaccharide which is usually attached to O-glycans on the surface of cells. It is known to play a role in cell-to-cell recognition processes. It is also a tumor marker used primarily in the management of pancreatic cancer. [1]
Tumor markers may be used for the following purposes: Monitoring the malignancy; When a malignant tumor is found by the presence of a tumor marker, the level of marker found in the body can be monitored to determine the state of the tumor and how it responds to treatment. If the quantity stays the same during treatment it can indicate that the ...
CA19-9 (carbohydrate antigen 19.9) is a tumor marker that is frequently elevated in pancreatic cancer. However, it lacks sensitivity and specificity, not least because 5% of people lack the Lewis (a) antigen and cannot produce CA19-9. It has a sensitivity of 80% and specificity of 73% in detecting pancreatic adenocarcinoma, and is used for ...
CA 242 is a tumor marker for sialylated Lewis carbohydrates associated with adenocarcinomas and e-selectin-mediated metastatic risk. [1] [2] [3] It is commonly tested along with CEA, CA19-9, and CA242 for detecting pancreatic cancer. [4] The specificity of CA 242 is higher than similar markers.
230099 Ensembl ENSG00000107159 ENSMUSG00000028463 UniProt Q16790 Q8VHB5 RefSeq (mRNA) NM_001216 NM_139305 RefSeq (protein) NP_001207 NP_647466 Location (UCSC) Chr 9: 35.67 – 35.68 Mb Chr 4: 43.51 – 43.51 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carbonic anhydrase IX (CA9/CA IX) is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase ...
[9] Serum from individuals with colorectal carcinoma often has higher levels of CEA than healthy individuals (above approximately 2.5ng/mL). [ 10 ] CEA measurement is mainly used as a tumor marker to monitor colorectal carcinoma treatment, to identify recurrences after surgical resection, for staging or to localize cancer spread through ...
[1] [7] [8] Radiomics emerged from the medical fields of radiology and oncology [3] [9] [10] and is the most advanced in applications within these fields. However, the technique can be applied to any medical study where a pathological process can be imaged.
M2-PK, as measured in feces, is a potential tumor marker for colorectal cancer.When measured in feces with a cutoff value of 4 U/ml, its sensitivity has been estimated to be 85% (with a 95% confidence interval of 65 to 96%) for colon cancer and 56% (confidence interval 41–74%) for rectal cancer. [1]