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pip (also known by Python 3's alias pip3) is a package-management system written in Python and is used to install and manage software packages. [4] The Python Software Foundation recommends using pip for installing Python applications and its dependencies during deployment. [5]
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Phosphatidylinositol 4,5-bisphosphate or PtdIns(4,5)P 2, also known simply as PIP 2 or PI(4,5)P 2, is a minor phospholipid component of cell membranes. PtdIns(4,5)P 2 is enriched at the plasma membrane where it is a substrate for a number of important signaling proteins. [1]
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Here, PIP3 has been implicated in regulating synaptic strengthening and AMPA expression, contributing to long-term potentiation. Moreover, PIP3 suppression disrupts normal AMPA expression on the neuron membrane and instead leads to the accumulation of AMPA on dendritic spines, commonly associated with synaptic depression .
Donald Trump was threatening to send Meta CEO Mark Zuckerberg to prison “for life” if he interfered in the election just a few short months ago—but come Thanksgiving, the bad blood appears ...
“I’m asking today, Joe Biden to please stop selling the wall,” the president-elect declared at a Mar-a-Lago press conference. “We’re going to use that to create a strong barrier.
Phosphatidylinositol 4,5-bisphosphate (PIP2) is an anionic signaling lipid. Its polyunsaturated acyl chains exclude it from GM1 lipid rafts. [5] [6] The multiple negative charges on PIP2 are thought to cluster proteins with positive charges residing in the plasma membrane leading to nanoscale clusters.