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Side effects from hormonal contraceptives typically disappear over time (3-5 months) with consistent use. [16] Less common effects of combined hormonal contraceptives include increasing the risk of deep vein thrombosis to 2-10 per 10,000 women per year and venous thrombotic events (see venous thrombosis) to 7-10 per 10,000 women per year. [15]
The most common side-effects of combined hormonal contraceptives include headache, nausea, breast tenderness, and breakthrough bleeding. Vaginal ring use can include additional side-effects including vaginal irritation and vaginal discharge. Contraceptive skin patch use can also include a side-effect of skin irritation around the patch site. [39]
The medication is available both alone and in combination with an estrogen. [11] [12] It is taken by mouth, used under the tongue, or by injection into a muscle or fat. [10] Common side effects include menstrual disturbances such as absence of periods, abdominal pain, and headaches. [10]
Drug-drug interactions among combined oral contraceptive pills and other medications of the user that decrease contraceptive estrogen and/or progestogen levels. [ 44 ] In any of these instances, a backup contraceptive method should be used until hormone active pills have been consistently taken for 7 consecutive days or drug-drug interactions ...
The incidence of certain side effects is different for the different formulations: for example, breakthrough bleeding is much more common with progestogen-only methods. Certain serious complications occasionally caused by estrogen-containing contraceptives are not believed to be caused by progestogen-only formulations: deep vein thrombosis is ...
Ormeloxifene may be used as a weekly oral contraceptive. [6] The weekly schedule is an advantage for women who prefer an oral contraceptive, but find it difficult or impractical to adhere to a daily schedule required by other oral contraceptives. For the first twelve weeks of use, it is advised to take the ormeloxifene pill twice per week. [6]
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