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The epiphyseal plate, epiphysial plate, physis, or growth plate is a hyaline cartilage plate in the metaphysis at each end of a long bone.It is the part of a long bone where new bone growth takes place; that is, the whole bone is alive, with maintenance remodeling throughout its existing bone tissue, but the growth plate is the place where the long bone grows longer (adds length).
It’s composed of highly active chondrocytes and responsible for longitudinal bone growth. Consequently, the bone elongates at this growth plate until closure occurs at skeletal maturity. At the end of an individual’s growth period, the production of new cartilage in the epiphyseal plate stops.
X-ray of a left hand, with automatic calculation of bone age by a computer software. Bone age is the degree of a person's skeletal development. In children, bone age serves as a measure of physiological maturity and aids in the diagnosis of growth abnormalities, endocrine disorders, and other medical conditions.
Linear growth takes place in the epiphyseal growth plates (EGP) of long bones. [23] In the growth plate, chondrocytes proliferate, hypertrophy and secrete cartilage extracellular matrix. New cartilage is subsequently remodeled into bone tissue, causing bones to grow longer. [24]
Bone is broken down by osteoclasts, and rebuilt by osteoblasts, both of which communicate through cytokine (TGF-β, IGF) signalling.Ossification (also called osteogenesis or bone mineralization) in bone remodeling is the process of laying down new bone material by cells named osteoblasts.
The metaphysis (pl.: metaphyses) is the neck portion of a long bone between the epiphysis and the diaphysis. [1] It contains the growth plate, the part of the bone that grows during childhood, and as it grows it ossifies near the diaphysis and the epiphyses.
During birth, fontanelles enable the bony plates of the skull to flex, allowing the child's head to pass through the birth canal. The ossification of the bones of the skull causes the anterior fontanelle to close over by 9 to 18 months. [3] The sphenoidal and posterior fontanelles close during the first few months of life.
Sever's disease, also known as calcaneus apophysitis, is an inflammation at the back of the heel (or calcaneus) growth plate in growing children. The condition is thought to be caused by repetitive stress at the heel. This condition is benign and common and usually resolves when the growth plate has closed or during periods of less activity.