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[2] [3] [4] It has an integrated spreadsheet for data input and can import files in several formats (Excel, SPSS, CSV, ...). MedCalc includes basic parametric and non-parametric statistical procedures and graphs such as descriptive statistics , ANOVA , Mann–Whitney test , Wilcoxon test , χ 2 test , correlation , linear as well as non-linear ...
An example of a Kaplan–Meier plot for two conditions associated with patient survival. The Kaplan–Meier estimator, [1] [2] also known as the product limit estimator, is a non-parametric statistic used to estimate the survival function from lifetime data. In medical research, it is often used to measure the fraction of patients living for a ...
Paul Meier (July 24, 1924 – August 7, 2011) [1] was a statistician who promoted the use of randomized trials in medicine. [2] [3]Meier is known for introducing, with Edward L. Kaplan, the Kaplan–Meier estimator, [4] [5] a method for measuring how many patients survive a medical treatment from one duration to another, taking into account that the sampled population changes over time.
The logrank test is based on the same assumptions as the Kaplan-Meier survival curve—namely, that censoring is unrelated to prognosis, the survival probabilities are the same for subjects recruited early and late in the study, and the events happened at the times specified. Deviations from these assumptions matter most if they are satisfied ...
The grey hash marks represent the observations in a particular sample drawn from that distribution, and the horizontal steps of the blue step function (including the leftmost point in each step but not including the rightmost point) form the empirical distribution function of that sample.
Another method of grouping the data is to use some qualitative characteristics instead of numerical intervals. For example, suppose in the above example, there are three types of students: 1) Below normal, if the response time is 5 to 14 seconds, 2) normal if it is between 15 and 24 seconds, and 3) above normal if it is 25 seconds or more, then the grouped data looks like:
Edward Lynn Kaplan (May 11, 1920 – September 26, 2006) [1] was a mathematician most famous for the Kaplan–Meier estimator, [2] developed together with Paul Meier. Biography [ edit ]
An example pipeline for analysis of FCM data and some of the Bioconductor packages relevant to each step. The process of moving from primary FCM data to disease diagnosis and biomarker discovery involves four major steps: Data pre-processing (including compensation, transformation and normalization) Cell population identification (a.k.a. gating)