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The female or male external sphincter muscle of urethra (sphincter urethrae): located in the deep perineal pouch, at the bladder's distal inferior end in females, and inferior to the prostate (at the level of the membranous urethra) in males. It is a secondary sphincter to control the flow of urine through the urethra.
The external sphincter muscle prevents urine leakage as the muscle is tonically contracted via somatic fibers that originate in Onuf's nucleus and pass through sacral spinal nerves S2-S4 then the pudendal nerve to synapse on the muscle. [7] [10] Voiding urine begins with voluntary relaxation of the external urethral sphincter.
Reported complications are mostly minor, and include: bleeding, perianal pain / discomfort (which may rarely be persistent), leakage of injected material, infection / abscess (which rarely may require drainage), mucosal erosion, obstructed defecation, hypersensitivity reaction, hematoma, diarrhea, pruritus ani, dermatitis, and bowel urgency ...
This is the first class of non-opioid pain medication approved to treat moderate to severe acute pain approved by the FDA in more than 20 years. The U.S. Food and Drug Administration (FDA) on ...
The FDA on Thursday approved a new class of pain medication that provides an alternative to opioids. It will be sold under the brand name Journavx. FDA approves new pain medication as an ...
FDA approves first new type of pain medication in 25 years. Brenda Goodman, CNN. January 30, 2025 at 6:29 PM. Suzetrigine is a prescription pill taken every 12 hours after a larger starter dose.
The internal urethral sphincter is a urethral sphincter muscle which constricts the internal urethral orifice. It is located at the junction of the urethra with the urinary bladder and is continuous with the detrusor muscle , [ 1 ] [ 2 ] but anatomically and functionally fully independent from it. [ 3 ]
The artificial urinary sphincter with a spring (2-component): cuff and pump unit. [3] [4] The cuff is placed around the urethra and the pump unit is inserted in the scrotum. The pressure in the hydraulic circuit is generated by the spring of the pump unit. The pressure in the retropubic space does not have any influence for this type of sphincter.