Search results
Results From The WOW.Com Content Network
26361 Ensembl ENSG00000198049 ENSMUSG00000026432 UniProt P47901 Q9WU02 RefSeq (mRNA) NM_000707 NM_011924 RefSeq (protein) NP_000698 NP_036054 Location (UCSC) Chr 1: 206.11 – 206.12 Mb Chr 1: 131.53 – 131.54 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Vasopressin V1b receptor (V1BR) also known as vasopressin 3 receptor (VPR3) or antidiuretic hormone receptor 1B is a protein ...
The human V 3 receptor (V 3 R, previously known as V 1B R) is a G-protein-coupled pituitary receptor that, because of its scarcity, was only recently characterized. [1] The 424-amino-acid sequence of the V 3 R has homologies of 45%, 39%, and 45% with the V 1 R, V 2 R and oxytocin receptor (OTR), respectively.
551 11998 Ensembl ENSG00000101200 ENSMUSG00000037727 UniProt P01185 P35455 RefSeq (mRNA) NM_000490 NM_009732 RefSeq (protein) NP_000481 NP_033862 Location (UCSC) Chr 20: 3.08 – 3.08 Mb Chr 2: 130.42 – 130.42 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The arginine vasopressin (AVP) gene is a gene whose product is proteolytically cleaved to produce vasopressin (also known as ...
Vasopressin agonists are used therapeutically in various conditions, and its long-acting synthetic analogue desmopressin is used in conditions featuring low vasopressin secretion, as well as for control of bleeding (in some forms of von Willebrand disease and in mild haemophilia A) and in extreme cases of bedwetting by children.
Conivaptan, sold under the brand name Vaprisol, is a non-peptide inhibitor of the receptor for anti-diuretic hormone, also called vasopressin. It was approved in 2004 for hyponatremia (low blood sodium levels). The compound was discovered by Astellas and marked in 2006. The drug is now marketed by Cumberland Pharmaceuticals, Inc.
Natriuretic peptides and their receptors have many different effects on the body, such as controlling blood pressure and helping bones grow. Each peptide has its own unique effects and interacts with specific receptors. Scientists have observed these effects by studying mice with specific natriuretic peptides or receptors removed. [3]
Vasopressin analogues are synthetic peptides structurally and functionally similar to arginine vasopressin (AVP), a naturally occurring hormone in mammals. These compounds have been developed to target specific vasopressin receptors ( V1 , V2 , and V3 ) with varying affinities, allowing for more tailored therapeutic applications.
Balovaptan (INN Tooltip International Nonproprietary Name; developmental code name RG7314), is a selective small molecule antagonist of the vasopressin V 1A receptor which is under development by Roche for the treatment of post-traumatic stress disorder. [1]