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Drugs can affect sperm parameters by inhibiting normal exocrine functions of the testes which can lead to a decrease in production of sperm, or by creating hormone imbalances. [4] For an example, anti-androgenic drugs like spironolactone, cimetidine, and ketoconazole can disrupt androgens in the glands and seminal tract to cause a decrease in ...
ASA production are directed against surface antigens on sperm, which can interfere with sperm motility and transport through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and impaired growth and development of the embryo.
Terms oligospermia, oligozoospermia, and low sperm count refer to semen with a low concentration of sperm [1] and is a common finding in male infertility. Often semen with a decreased sperm concentration may also show significant abnormalities in sperm morphology and motility (technically oligoasthenoteratozoospermia ).
Hypogonadism can involve just hormone production or just fertility, but most commonly involves both. [citation needed] Examples of hypogonadism that affect hormone production more than fertility are hypopituitarism and Kallmann syndrome; in both cases, fertility is reduced until hormones are replaced but can be achieved solely with hormone ...
Azoospermia is the medical condition of a man whose semen contains no sperm. [1] It is associated with male infertility, but many forms are amenable to medical treatment.In humans, azoospermia affects about 1% of the male population [2] and may be seen in up to 20% of male infertility situations in Canada.
It decreases the sperm quality and is therefore one of the major causes of infertility or reduced fertility in men. A method to increase the chance of pregnancy is ICSI . [ 1 ] The percentage of viable spermatozoa in complete asthenozoospermia varies between 0 and 100%.
Sperm count and morphology can be calculated by microscopy. Sperm count can also be estimated by kits that measure the amount of a sperm-associated protein, and are suitable for home use. [30] [unreliable medical source?] Computer assisted semen analysis (CASA) is a catch-all phrase for automatic or semi-automatic semen analysis techniques.
Male reproductive function declines with increasing age as indicated by decreased sperm quality and fertility. [25] As rats age, undifferentiated spermatogonial cells undergo numerous changes in gene expression. [26] These changes include upregulation of several genes involved in the DNA damage response.