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The Vacanti mouse. The Vacanti mouse was a laboratory mouse (circa 1996) [1] that had what looked like a human ear grown on its back. The "ear" was actually an ear-shaped cartilage structure grown by seeding cow cartilage cells into biodegradable ear-shaped mold and then implanted under the skin of the mouse, with an external ear-shaped splint to maintain the desired shape.
Vacanti was born in Omaha, Nebraska in 1948, the oldest of four brothers who are also scientists: Charles Vacanti, Martin, and Francis. [7] [8] Following education at Creighton University and the University of Nebraska (MD 1974 [9]), Vacanti trained in surgery at the Massachusetts General Hospital in Boston, MA, Boston Children's Hospital, and further specialized in transplantation at the ...
He is known for the Vacanti mouse, a mouse created with Linda Griffith and Joseph Upton with cartilage shaped like a human ear on its back, and for being the senior author on the first of two retracted articles on STAP cells, a concept proposed by his brother and himself, and co-authored with Haruko Obokata.
As an assistant professor, she joined a collaboration with Charles Vacanti, Joseph Vacanti, and Joseph Upton to create tissue engineered cartilage in the shape of a human ear (published under the surname used in her first marriage), known as the Vacanti mouse. [6]
Vacanti mouse; This page was last edited on 14 March 2021, at 03:57 (UTC). Text is available under the Creative Commons Attribution-ShareAlike 4.0 ...
Charles Vacanti continued to work on these cells when he moved to Harvard, including with thoracic surgeon Koji Kojima who identified them in lung tissue. [3] Working with a graduate student Haruko Obokata in his lab at Harvard from 2008, Vacanti later refined this theory to suggest that stress or injury could actually trigger the development of pluripotency in somatic cells.
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Charles Vacanti, Anasthesiologist; Tissue engineering; Stem Cells; Known for the Vacanti Mouse; Arthur K. Wheelock Jr., an Uxbridge native, was curator of Dutch painting at the National Gallery of Art in Washington, D.C. from 1975 [51] to 2018.