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Death rate from obesity, 2019. Obesity is a risk factor for many chronic physical and mental illnesses.. The health effects of being overweight but not obese are controversial, with some studies showing that the mortality rate for individuals who are classified as overweight (BMI 25.0 to 29.9) may actually be lower than for those with an ideal weight (BMI 18.5 to 24.9). [1]
The Women's Health Initiative (WHI) was a series of clinical studies initiated by the U.S. National Institutes of Health (NIH) in 1991, to address major health issues causing morbidity and mortality in postmenopausal women. It consisted of three clinical trials (CT) and an observational study (OS).
As a result of pressure from HIV-infected men in the gay community, [citation needed] who demanded better access to clinical trials, the U.S. Congress passed the Health Omnibus Programs Extension Act of 1988 (Public Law 100-607) [2] which mandated the development of a database of AIDS Clinical Trials Information Services (ACTIS). [3]
According to a 2015 study, fat people who feel discriminated against have shorter life expectancies than fat people who don't. “These findings suggest the possibility that the stigma associated with being overweight,” the study concluded, “is more harmful than actually being overweight.”
The Center for Information and Study on Clinical Research Participation is hosting a seminar to spread awareness about the benefits of Black people joining clinical trials on Nov. 17, 2022 at ...
Both overweight and obesity are major risk factors for cardiovascular diseases, specifically heart disease and stroke, and diabetes. The International Diabetes Federation reports that as of 2011 [needs update], 366 million people have diabetes; this number is projected to increase to over half a billion (estimated 552 million) by 2030.
Despite representing 50% of the U.S. population, women are generally underrepresented in clinical trials. For example, women represent 38.2% of participants in cardiovascular clinical trials. When ...
In one study that examined people over 15 years, 11% of those with MASH developed cirrhosis as compared to less than 1% of people with MASLD. [126] Other estimates have shown that MASLD and MASH were found to worsen with cirrhosis in respectively 2–3% and 15–20% of the people over a 10–20 year period. [13]
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