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The risk of enlarged ventricles on brain scan (associated with schizophrenia symptoms and biologically suggestive of Emil Kraepelin's dementia praecox) was greatly increased if the subjects had both a higher genetic load for schizophrenia and lower birthweight. The investigators suggested that in utero insults may specifically stress those with ...
Estimates of the heritability of schizophrenia are between 70% and 80%, which implies that 70% to 80% of the individual differences in risk of schizophrenia are associated with genetics. [ 21 ] [ 84 ] These estimates vary because of the difficulty in separating genetic and environmental influences, and their accuracy has been queried.
Expressed emotion (EE), is a measure of the family environment that is based on how the relatives of a psychiatric patient spontaneously talk about the patient. [1] It specifically measures three to five aspects of the family environment: the most important are critical comments, hostility, emotional over-involvement, with positivity and warmth sometimes also included as indications of a low ...
However, though the risk of violence in schizophrenia is small the association is consistent, and there are minor subgroups where the risk is high. [48] This risk is usually associated with a comorbid disorder such as a substance use disorder - in particular alcohol, or with antisocial personality disorder. [48]
This disease has been found to be correlated with the season of birth. It's known that individuals with the disease are more likely to born in the winter months. Though the relative risk is small, persons born in the winter months are about 10% more likely to develop schizophrenia than those who are born within the summer months. [23]
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.