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  2. Antigen presentation - Wikipedia

    en.wikipedia.org/wiki/Antigen_presentation

    Whenever they encounter signs of disease, caused for example by the presence of viruses or intracellular bacteria or a transformed tumor cell, they initiate processes to destroy the potentially harmful cell. [1] All nucleated cells in the body (along with platelets) display class I major histocompatibility complex (MHC-I molecules). Antigens ...

  3. Transudate - Wikipedia

    en.wikipedia.org/wiki/Transudate

    Transudate is extravascular fluid with low protein content and a low specific gravity (< 1.012). It has low nucleated cell counts (less than 500 to 1000 per microliter) and the primary cell types are mononuclear cells: macrophages, lymphocytes and mesothelial cells. For instance, an ultrafiltrate of blood plasma is transudate.

  4. Antigen processing - Wikipedia

    en.wikipedia.org/wiki/Antigen_processing

    Langerhans' cells are particular type of dendritic cells present in non lymphoid tissues together with interstitial cells. When these cells (in an immature state) come in contact with antigenic cells or disease causing viruses etc. these cells produce an inflammatory stimulus and start antigen processing and move toward lymph nodes where these ...

  5. Antigen-presenting cell - Wikipedia

    en.wikipedia.org/wiki/Antigen-presenting_cell

    Antigen presentation stimulates immature T cells to become either mature "cytotoxic" CD8+ cells or mature "helper" CD4+ cells. An antigen-presenting cell (APC) or accessory cell is a cell that displays an antigen bound by major histocompatibility complex (MHC) proteins on its surface; this process is known as antigen presentation.

  6. Buffy coat - Wikipedia

    en.wikipedia.org/wiki/Buffy_coat

    Human blood after separation by centrifugation. Plasma (upper layer), buffy coat (middle, white-colored layer) and erythrocyte (red blood cell) layer (bottom) can be seen. The buffy coat is commonly used for DNA extraction, [4] with leukocytes providing approximately 10 times more concentrated sources of nucleated cells. [5]

  7. MHC class I - Wikipedia

    en.wikipedia.org/wiki/MHC_class_I

    MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of vertebrates. [1] [2] They also occur on platelets, but not on red blood cells.

  8. Cytocentrifuge - Wikipedia

    en.wikipedia.org/wiki/Cytocentrifuge

    The cytocentrifugation process can cause cells to appear distorted. Cells located at the centre of the smear may look compressed compared to cells at the periphery. Cell nuclei may develop artifactual clefts, lobes, or holes, [4] and the cytoplasm may appear vacuolated or develop irregular projections. Cytoplasmic granules may be pushed to the ...

  9. Megakaryocyte - Wikipedia

    en.wikipedia.org/wiki/Megakaryocyte

    Once the cell has completed differentiation and become a mature megakaryocyte, it begins the process of producing platelets. The maturation process occurs via endomitotic synchronous replication whereby the cytoplasmic volume enlarges as the number of chromosomes multiplies without cellular division.