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Otomycosis commonly worsens from overuse of antibacterial ear drops, which should never be used for more than 7 days. In such cases the fungus is an opportunist that results from antibacterial suppression of the normal bacterial flora, combined with the steroid the drops also contain.
Ear drops should not be shared to prevent the spread of infection. [7] Ear drops should not be used after the expiration date. [7] Ear drops should only be used in the affected ear. Ear drops are usually used for a short duration of time. Make sure to only use it as prescribed. [7]
Normal ear drum. A perforated eardrum (tympanic membrane perforation) is a prick in the eardrum. It can be caused by infection (otitis media), trauma, overpressure (loud noise), inappropriate ear clearing, and changes in middle ear pressure. An otoscope can be used to view the eardrum to diagnose a perforation. Perforations may heal naturally ...
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Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
Gentamicin is a type of aminoglycoside [5] and works by disrupting the ability of the bacteria to make proteins, which typically kills the bacteria. [5] Gentamicin is naturally produced by the bacterium Micromonospora purpurea, [9] [5] was patented in 1962, approved for medical use in 1964. [10]