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  2. Scopolamine - Wikipedia

    en.wikipedia.org/wiki/Scopolamine

    The effects of scopolamine were studied for use as a truth serum in interrogations in the early 20th century, [62] but because of the side effects, investigations were dropped. [63] In 2009, the Czechoslovak state security secret police were proven to have used scopolamine at least three times to obtain confessions from alleged antistate ...

  3. Hyoscine butylbromide - Wikipedia

    en.wikipedia.org/wiki/Hyoscine_butylbromide

    It is a quaternary ammonium compound and a semisynthetic derivative of hyoscine hydrobromide (scopolamine). The attachment of the butyl-bromide moiety effectively prevents the movement of this drug across the blood–brain barrier, effectively minimising undesirable central nervous system side effects associated with scopolamine/hyoscine. [25]

  4. Muscarinic antagonist - Wikipedia

    en.wikipedia.org/wiki/Muscarinic_antagonist

    However, scopolamine has greater effects on the central nervous system (CNS) than atropine due to its ability to cross the blood–brain barrier. [4] At higher-than-therapeutic doses, atropine and scopolamine cause CNS depression characterized by amnesia, fatigue, and reduction in rapid eye movement sleep.

  5. Cholinergic blocking drug - Wikipedia

    en.wikipedia.org/wiki/Cholinergic_blocking_drug

    The name Belladonna, meaning beautiful ladies, was derived from women using berry juice from the plant cosmetically to dilate their pupils. [ 4 ] The mydriatic effect was studied by the German chemist Friedlieb Ferdinand Runge (1795-1867), in which the active ingredient, atropine , was first discovered by Vaquelin in 1809 and was first isolated ...

  6. Sominex - Wikipedia

    en.wikipedia.org/wiki/Sominex

    In July 1975, the J. B. Williams Co. began marketing Sominex 2. [37] On November 24, 1975, Attorney General Evelle J. Younger filed suit on behalf of the State of California against Williams Co., stating that the product did not warn against use by pregnant or nursing women or persons with asthma or COPD, nor did it notify consumers that it should not be used in conjunction with alcohol. [38]

  7. Bellergal - Wikipedia

    en.wikipedia.org/wiki/Bellergal

    Common side effects of bellergal include drowsiness, flushing, nausea, vomiting, diarrhea, constipation, decreased sweating, visual disturbances, unusual fatigue or weakness and dry mouth. [ 3 ] [ 4 ] Bellergal has a high potential for potentially serious drug interactions due to strong CYP3A4 inhibition by ergotamine .

  8. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    When taken with Cialis, alpha-blockers can cause a drop in blood pressure. These medications are frequently prescribed to manage high blood pressure, benign prostatic hyperplasia (enlarged ...

  9. Twilight sleep - Wikipedia

    en.wikipedia.org/wiki/Twilight_sleep

    The two presented their findings on the use of scopolamine during childbirth at the 1906 National Obstetrics Conference in Berlin, Germany. [8] They recorded preferred dosages and adverse side effects of scopolamine, which included slowed pulse, bradypnea, delirium, dilated pupils, flushed skin, and thirst. [7] [8]