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Fluphenazine, sold under the brand name Prolixin among others, is a high-potency typical antipsychotic medication. [2] It is used in the treatment of chronic psychoses such as schizophrenia , [ 2 ] [ 3 ] and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine . [ 4 ]
10. You're taking medications that cause weight gain "Certain medications can induce weight gain or hinder weight loss by altering hormones, changing appetite, or causing water retention," says Costa.
“There are many medications that may cause weight gain,” says W. Scott Butsch, M.D., director of obesity medicine in the Bariatric and Metabolic Institute at the Cleveland Clinic.
“Eating within a specific timeframe can help avoid late-night snacking, which often contributes to an excess consumption of calories, which is a common cause of weight gain,” Collins says ...
The development of 5-HT 2C receptor knockout mice in the mid-1990s was a hallmark achievement in the identification and development of serotonergic drugs for weight loss. These knockout mice were hyperphagic , which led to obesity, partial Leptin resistance, increased adipose deposition, insulin resistance, and impaired glucose tolerance.
Both generations of medication tend to block receptors in the brain's dopamine pathways, but atypicals at the time of marketing were claimed to differ from typical antipsychotics in that they are less likely to cause extrapyramidal symptoms (EPS), which include unsteady Parkinson's disease-type movements, internal restlessness, and other ...
When it comes to weight loss, people on semaglutide typically lose anywhere between half a pound to two pounds per week, says Dr. Kumar. The amount of weight you lose depends on many factors ...
It has only low and likely clinically unimportant affinity for the serotonin 5-HT 2C receptor, which may underlie its low propensity for appetite stimulation and weight gain. [ 67 ] [ 75 ] [ 76 ] The drug also has negligible affinity for the histamine H 1 receptor and the muscarinic acetylcholine receptors , and hence has no antihistamine or ...