Search results
Results From The WOW.Com Content Network
Synergists are muscles that facilitate the fixation action. There is an important difference between a helping synergist muscle and a true synergist muscle. A true synergist muscle is one that only neutralizes an undesired joint action, whereas a helping synergist is one that neutralizes an undesired action but also assists with the desired action.
The isoflavone phytoestrogens genistein and daidzein are non-selective ERR agonists, [27] while XCT790 has been identified as a potent and selective inverse agonist of ERRα. [28] SLU-PP-332 is a potent agonist of ERRα. [29] Cholesterol has recently been found to bind to and activate the ERRα, and may be the endogenous ligand for the receptor ...
They are named because of sequence homology with estrogen receptors, but do not appear to bind estrogens or other tested steroid hormones. There are three human estrogen related receptors: ERRα ; ERRβ ; ERRγ ; ERRs bind enhancers throughout the genome where they exert effects on gene regulation.
A co-agonist works with other co-agonists to produce the desired effect together. NMDA receptor activation requires the binding of both glutamate, glycine and D-serine co-agonists. Calcium can also act as a co-agonist at the IP3 receptor. A selective agonist is selective for a specific type of receptor. E.g.
Muscle coactivation occurs when agonist and antagonist muscles (or synergist muscles) surrounding a joint contract simultaneously to provide joint stability, [1] [2] and is suggested to depend crucially on supraspinal processes involved in the control of movement. [3]
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor (mainly found as a chromatin-binding protein [5]) that is activated by the sex hormone estrogen.
Estradiol is an estrogen, or an agonist of the nuclear estrogen receptors (ERs), the estrogen receptor alpha (ERα) and the estrogen receptor beta (ERβ). [1] [2] [6] In one study, the EC 50 Tooltip half-maximal effective concentration value of estradiol for the human ERα was 50 pM (0.05 nM) and for the human ERβ was 200 pM (0.2 nM).
The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. [4] [5] In humans, the oxytocin receptor is encoded by the OXTR gene [6] [7] which has been localized to human chromosome 3p25. [8] Evolutionary tree of the oxytocin, vasotocin, mesotocin and isotocin receptors and ...