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Norgestimate, sold under the brand name Ortho Tri-Cyclen among others, is a progestin medication which is used in birth control pills for women and in menopausal hormone therapy. [1] [3] [4] [5] The medication is available in combination with an estrogen and is not available alone. [6] It is taken by mouth. [1]
Norethindrone acetate and ethinyl estradiol have been approved in the US for the prevention of pregnancy as a swallowable tablet since 1968. [5] In 2022, the combination of ethinylestradiol with norethisterone or with norethisterone acetate was the 80th most commonly prescribed medication in the United States, with more than 8 million ...
In addition, there is a single preparation (brand name FemHRT) containing very low doses of EE (2.5 and 5 μg) plus a progestin in an oral tablet that remains in use for menopausal hormone therapy. [ 12 ] [ 20 ] EE was previously available by itself under brand names like Estinyl and Lynoral in the form of 0.002, 0.01, 0.02, 0.025, 0.05, 0.1, 0 ...
Estradiol/progesterone (TX-001HR), a combination of estradiol and progesterone in oil-filled capsules, is currently pending approval. [45] Estradiol and norgestimate (Prefest; 1 mg / 90 μg) was previously available in the U.S. but was discontinued.
NETA is available in the form of tablets for use by mouth both alone and in combination with estrogens including estradiol, estradiol valerate, and ethinylestradiol. [16] [4] Transdermal patches providing a combination of 50 μg/day estradiol and 0.14 or 0.25 mg/day NETA are available under the brand names CombiPatch and Estalis.
Co-cyprindiol, a shortened form of combination of cyproterone acetate and ethinylestradiol, is a generic name of EE/CPA. [ 25 ] [ 26 ] [ 27 ] It is also known by its former developmental code names SHB 209 AB (Diane) [ 28 ] [ 21 ] [ 29 ] and SHB 209 AE (Diane-35).