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First, in the "precalcific stage", something causes tendon cells to transform into other cells that can act as sites for calcium deposition. [2] This is followed by the two-part "calcific stage"; first calcium is deposited (the formative phase), then the body begins to break down the calcium deposit (the resorptive phase). [ 2 ]
One of the principal causes of arterial stiffening with age is vascular calcification. Vascular calcification is the deposition of mineral in the form of calcium phosphate salts in the smooth muscle-rich medial layer of large arteries including the aorta. DNA damage, especially oxidative DNA damage, causes accelerated vascular calcification. [11]
The plasma total calcium concentration is in the range of 2.2–2.6 mmol/L (9–10.5 mg/dL), and the normal ionized calcium is 1.3–1.5 mmol/L (4.5–5.6 mg/dL). [4] The amount of total calcium in the blood varies with the level of plasma albumin, the most abundant protein in plasma, and therefore the main carrier of protein-bound calcium in the blood.
Calcium supplements may be a bonus for bone health. But if you’re taking these medications, your supplement might backfire. 5 Ways Your Calcium Supplement May Interact with Medications ...
Doctors reveal the most important foods to avoid to reduce swelling.
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