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Metronidazole is thought to work by first diffusing into the cytoplasm of the anaerobic bacteria where it is then activated and reduced into a short-lived nitroso free radical which can interact with DNA, causing a loss of the helical DNA structure, strand breakage, and bacterial death.
How it works. Metronidazole is an antibiotic that may be used in the treatment of anaerobic infections caused by susceptible bacteria or parasites. Anaerobic means "living without air".
Metronidazole diffuses into the organism, inhibits protein synthesis by interacting with DNA, and causes a loss of helical DNA structure and strand breakage. Therefore, it causes cell death in susceptible organisms. The mechanism of action of metronidazole occurs through a four-step process.
Metronidazole is used to treat bacterial infections in different areas of the body. It is also used to treat infections caused by protozoa (eg, trichomoniasis and amebiasis) and infections caused by bacteria that do not need oxygen to survive.
Why is this medication prescribed? Metronidazole is used to treat infections of the reproductive system, gastrointestinal (GI) tract, skin, heart, bone, joint, lung, blood, nervous system, and other areas of the body. It is also used to treat certain sexually transmitted diseases (STDs).
Uses. Metronidazole is an antibiotic that is used to treat a wide variety of infections. It works by stopping the growth of certain bacteria and parasites.This antibiotic treats...
Medical uses. A tube of metronidazole cream. Metronidazole has activity against some protozoans and most anaerobic bacteria (both Gram-negative and Gram-positive classes) but not the aerobic bacteria. [18][19]
Metronidazole is a nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
How does metronidazole work? When will I feel better? What if I do not get better? Will it give me thrush? Will it affect my contraception? Can I drive or ride a bike? Can I drink alcohol while taking metronidazole? Is there any food or drink I need to avoid? Page last reviewed: 17 November 2021. Next review due: 17 November 2024.
Pregnancy & Breastfeeding. What Else to Know. Comments. More. Generic Name: metronidazole. Brand Names: Flagyl, Flagyl ER, Metro IV (discontinued), Metromidol (discontinued), Protostat (discontinued), and Satric (discontinued) Drug Class: Nitroimidazoles. What is metronidazole, and what is it used for?