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Chr. 11 p15.5. Hemoglobin (haemoglobin, [ a ]Hb or Hgb) is a protein containing iron that facilitates the transport of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, [ 3 ] with the sole exception of the fish family Channichthyidae. [ 4 ]
Each hemoglobin molecule carries four heme groups; hemoglobin constitutes about a third of the total cell volume. Hemoglobin is responsible for the transport of more than 98% of the oxygen in the body (the remaining oxygen is carried dissolved in the blood plasma). The red blood cells of an average adult human male store collectively about 2.5 ...
Under normal conditions in adult humans at rest, hemoglobin in blood leaving the lungs is about 98–99% saturated with oxygen, achieving an oxygen delivery between 950 and 1150 ml/min [25] to the body. In a healthy adult at rest, oxygen consumption is approximately 200–250 ml/min, [25] and deoxygenated blood returning to the lungs is still ...
The oxygen–hemoglobin dissociation curve, also called the oxyhemoglobin dissociation curve or oxygen dissociation curve (ODC), is a curve that plots the proportion of hemoglobin in its saturated (oxygen-laden) form on the vertical axis against the prevailing oxygen tension on the horizontal axis. This curve is an important tool for ...
Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. [ 1 ] Hypoxia may be classified as either generalized, affecting the whole body, or local, affecting a region of the body. [ 2 ] Although hypoxia is often a pathological condition, variations in arterial oxygen ...
Venous oxygen saturation (SvO 2) is the percentage of oxygenated hemoglobin returning to the right side of the heart. It can be measured to see if oxygen delivery meets the tissues' demands. SvO 2 typically varies between 60% and 80%. [9] A lower value indicates that the body is in lack of oxygen, and ischemic diseases occur.
Definition. Hypoxemia refers to the low level of oxygen in blood, and the more general term hypoxia is an abnormally low oxygen content in any tissue or organ, or the body as a whole. [2] Hypoxemia can cause hypoxia (hypoxemic hypoxia), but hypoxia can also occur via other mechanisms, such as anemia. [4]
A blood cell (also called a hematopoietic cell, hemocyte, or hematocyte) is a cell produced through hematopoiesis and found mainly in the blood. Major types of blood cells include red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes). Together, these three kinds of blood cells add up to a total 45% of the ...