Search results
Results From The WOW.Com Content Network
Glycerol 1-phosphate, sometimes called as D-glycerol 3-phosphate, is the enantiomer of glycerol 3-phosphate. Eukaryotes use the 3-phosphate, or L-configuration, for glycerolipid backbone. The 1-phosphate is specifically found in archeal lipids. [5]
Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (a.k.a. glycerone phosphate, outdated) to sn-glycerol 3-phosphate. [2] Glycerol-3-phosphate dehydrogenase serves as a major link between carbohydrate metabolism and lipid metabolism.
The glycerol phosphate shuttle was first characterized as a major route of mitochondrial hydride transport in the flight muscles of blow flies. [5] [6] It was initially believed that the system would be inactive in mammals due to the predominance of lactate dehydrogenase activity over glycerol-3-phosphate dehydrogenase 1 (GPD1) [5] [7] until high GPD1 and GPD2 activity were demonstrated in ...
When dihydroxyacetone phosphate is produced, glyceroneogenesis will branch off from gluconeogenesis. [1] With the expense of NADH, dihydroxyacetone phosphate will convert to glycerol 3-phosphate, which is the final product of glyceroneogenesis. In addition, triglyceride can be generated by re-esterifying 3 fatty acid chains on glycerol 3-phosphate.
Glycerol phosphate may refer to: Glycerol 1-phosphate; Glycerol 2-phosphate; Glycerol 3-phosphate This page was last edited on 31 May 2018 ...
In enzymology, a glycerol-3-phosphate cytidylyltransferase (EC 2.7.7.39) is an enzyme that catalyzes the chemical reaction. CTP + sn-glycerol 3-phosphate diphosphate + CDP-glycerol. Thus, the two substrates of this enzyme are CTP and sn-glycerol 3-phosphate, whereas its two products are diphosphate and CDP-glycerol.
The majority of triglycerides are synthesised from glycerol 3-phosphate (G3P) via the addition of three fatty acyl-CoA substrates, which are made from fatty acids. The first of these additions is catalysed by glycerol-3-phosphate acyltransferases (GPATs: EC 2.3.1.15), including GPAT4, yielding lysophosphatidic acid. [7]
The 3 substrates of this enzyme are ATP, H 2 O, and glycerol-3-phosphate, whereas its 3 products are ADP, phosphate, and glycerol-3-phosphate. This enzyme belongs to the family of hydrolases , specifically those acting on acid anhydrides to catalyse transmembrane movement of substances.