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They found that, over a 3-year period, people with the highest levels of xylitol in their blood had double the risk of heart attack, stroke, and death compared to those with the lowest levels.
A common low-calorie sweetener called xylitol, found in gum, candy, toothpaste and more, may cause clots that can lead to heart attack and stroke, a new study found.
The researchers also wanted to understand the mechanism at work, so they fed xylitol to mice, added it to blood and plasma in a lab and gave a xylitol-containing drink to 10 healthy volunteers.
Xylitol is used as a sugar substitute in such manufactured products as drugs, dietary supplements, confections, toothpaste, and chewing gum, but is not a common household sweetener. [5] [7] [15] Xylitol has negligible effects on blood sugar because its assimilation and metabolism are independent of insulin. [15]
Some of the less significant adverse effects of laxative abuse include dehydration (which causes tremors, weakness, fainting, blurred vision, kidney damage), low blood pressure, fast heart rate, postural dizziness and fainting; [26] however, laxative abuse can lead to potentially fatal acid-base, and electrolyte imbalances. [26]
Primary or functional constipation is defined by ongoing symptoms for greater than six months not due to an underlying cause such as medication side effects or an underlying medical condition. [ 2 ] [ 19 ] It is not associated with abdominal pain, thus distinguishing it from irritable bowel syndrome . [ 2 ]
The researchers measured levels of xylitol in participants' blood after an overnight fast, and found that those with the highest levels had a two-fold greater risk of having a heart attack, stroke ...
Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...